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are concise point-of-care prescribing, dosing and administering information to Prior to the initial foscarnet infusion, establish diuresis by administering Prehydrate with mL NS or D5W before first infusion to decrease risk for nephrotoxicity. See prescribing information for dose adjustments for CrCl < Group: antiviral. Solution for injection, 24 mg/ml ml, ml [non-EDL]. General information. Foscarnet is a non-nucleoside pyrophosphate analogue given.

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Foscavir is not recommended during pregnancy. Lamivudine; Tenofovir Disoproxil Fumarate: Minor Previous treatment with nephrotoxic agents, like foscarnet, may result in decreased bleomycin clearance if renal function has been impaired. Lumiracoxib The risk or severity of nephrotoxicity can be increased when Lumiracoxib is combined with Foscarnet.

Ajmaline The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Ajmaline.

Bromazepam Foscarnet may decrease the excretion rate of Bromazepam which could result in a higher serum level. However, the data was insufficient to define the potential teratogenicity of foscarnet in humans at the dosages used. Donepezil is considered a drug with a known risk of TdP.

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Major When possible, avoid concurrent use of foscarnet with other drugs known to prolong the QT interval, such as azithromycin.

Major When possible, avoid concurrent use of foscarnet with other drugs known to prolong the QT interval, such as maprotiline. The safety and efficacy of foscarnet in children have not been established. Lopinavir; ritonavir is also associated with QT prolongation. Pentastarch Foscarnet informxtion decrease the excretion rate of Pentastarch which could result in a higher serum level.

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The HIV guidelines suggest foscarnnet as second-line induction therapy; induction should be followed-up with chronic maintenance therapy secondary prophylaxis. Antivirals for systemic use; direct acting antivirals; phosphonic acid prescrubing, ATC code: Both QT prolongation and torsade de pointes TdP have been reported during postmarketing use of foscarnet; concentration-dependent QTc prolongation has also occurred during clinical trials of osimertinib.

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Foscarnet Injection: MedlinePlus Drug Information

Cariporide The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Cariporide. Due to the extremely long half-life of informtaion, a drug interaction is possible for days to weeks after discontinuation of amiodarone. Nelfinavir The risk or severity of QTc prolongation can be increased when Nelfinavir is combined with Foscarnet. Foscarnet is administered by slow intravenous infusion. Major When possible, avoid concurrent use of foscarnet with other drugs known to prolong the QT interval, such as arsenic trioxide.

Fluspirilene The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Fluspirilene. Blonanserin Foscarnet may decrease the excretion rate of Blonanserin foscarrnet could result in a higher serum level.

Keep all appointments with your doctor, including your eye doctor, and the laboratory. Mesalazine The risk or severity of nephrotoxicity can be increased when Mesalazine is combined with Foscarnet. Desflurane The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Desflurane.

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Pazopanib has also been reported to prolong the QT interval. According to the manufacturer, it is unknown if foscarnet is distributed into breast milk.

Baclofen Foscarnet may decrease the excretion rate of Baclofen which could result in a higher serum level. Risperidone has also been associated with a possible risk for QT prolongation and TdP.

To view the changes to a medicine you must sign up and log in. Alprazolam Foscarnet may decrease the excretion rate of Alprazolam which could result in a higher serum level.

Amrinone Foscarnet may decrease the excretion rate of Amrinone which could result in a higher serum level.

Foscarnet Injection

Because of the potential for TdP, use of foscarnet with dofetilide is contraindicated. Gallium Ga 68 Dotatate: Cefprozil The risk or severity of nephrotoxicity can be increased when Cefprozil is combined with Foscarnet. Patients predisposed to acute renal failure include patients receiving known nephrotoxic drugs like foscarnet. Ampicillin Foscarnet may decrease the excretion rate of Ampicillin which could result in a higher inflrmation level.

Major When possible, avoid concurrent use of foscarnet with other drugs known to prolong the QT interval, such as propafenone.

In addition, dose-related increases in mean QTc and heart rate were observed in healthy subjects.